Human beings are 99.9% genetically identical. The differences not only determine our appearance and abilities, but also our susceptibility to disease. A primary goal of our research group is to develop statistical tools for finding associations between patterns of genetic variation and complex disease. Data arises from primarily from Next Generation Sequencing and gene expression arrays. Our methodological work is motivated by our studies of schizophrenia, autism and other genetic disorders. We are also interested in the population genetics of human gene diversity.