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Interpretation of Regression Coefficients

The output below presents part of the S-Plus output listing the estimates of the regressions coefficients and their standard errors. We see that the coefficients for gender, length-of-stay, and the WAB score at discharge are all significantly related to the probability of spontaneous language recovery at the 0.05 level. The coefficient for length-of-stay is negative indicating that the longer patients are in the hospital the smaller the chance of spontaneous language recovery relative to patients who have shorter lengths-of-stay even after controlling for the effect of the WAB1 score. The coefficient for WAB1 is positive as we would expect. Males, after controlling for the other variables in the model, are times as likely to recover spontaneous language function as females. A 95% confidence interval for , the adjusted log odds ratio of recovery for males relative to females, however, is large and ranges from 0.47 to 5.29. We also note that side of stroke and subject's age do not have a statistically significant association with spontaneous language recovery after controlling for the effects of the other variables. Details about these tests can be found in Hosmer and Lemeshow (1989, Chapter 5).

402 > stroke <- read.table("stroke.dat", head=T) 
402 > stroke[1:10,]
   Side Gender Age LOSD WAB1 Status 
 1    0      0  79   27 18.2      0
 2    0      0  82   17 86.0      0
 3    1      0  72   42 46.3      0
 4    0      0  59   23 35.6      0
 5    0      0  60   28  0.0      0
 6    1      1  75   12 81.9      1
 7    0      0  75   53 56.0      0
 8    0      0  85   46 17.3      0
 9    0      0  79   58 74.9      0
10    0      1  82   34 18.2      0

402 > mymod <- glm(Status ~ Side + Gender + Age + LOSD +WAB1, family=binomial,
+ data=stroke)  

402 > summary(mymod)

Call: glm(formula = Status ~ Side + Gender + Age + LOSD + WAB1, family = binomial, 
        data = stroke)
Deviance Residuals:
       Min         1Q       Median            3Q      Max 
 -1.317524 -0.2999725 -0.003778562 -0.0002212266 2.862154

Coefficients:
                    Value Std. Error    t value 
(Intercept) -11.072759221 6.28633143 -1.7614024
       Side  -1.369026127 1.10318267 -1.2409786
     Gender   2.876569185 1.25325078  2.2952862
        Age  -0.006938071 0.03062231 -0.2265691
       LOSD  -0.196137069 0.09595028 -2.0441532
       WAB1   0.164467235 0.07172681  2.2929674

(Dispersion Parameter for Binomial family taken to be 1 )

    Null Deviance: 65.71913 on 60 degrees of freedom

Residual Deviance: 28.9878 on 55 degrees of freedom

Number of Fisher Scoring Iterations: 7 

Correlation of Coefficients:
       (Intercept)       Side     Gender        Age       LOSD 
  Side  0.2553975                                             
Gender -0.5007016  -0.2793548                                 
   Age -0.3373404  -0.1265137  0.2006563                      
  LOSD  0.1199385   0.2046374 -0.5309336 -0.1894954           
  WAB1 -0.9292116  -0.3055970  0.5278826  0.0616042 -0.2969773
402 > anova(mymod)
Analysis of Deviance Table

Binomial model

Response: Status

Terms added sequentially (first to last)
       Df Deviance Resid. Df Resid. Dev 
  NULL                    60   65.71913
  Side  1  0.10011        59   65.61902
Gender  1  3.36010        58   62.25892
   Age  1  1.45449        57   60.80444
  LOSD  1 12.25425        56   48.55018
  WAB1  1 19.56238        55   28.98780
402 >



Brian Junker
Sun Mar 15 22:19:21 EST 1998