From: brian [brian@stat.cmu.edu] Sent: Monday, April 30, 2007 3:52 PM To: 'acrosset@stat.cmu.edu'; 'Steve Wasik' Subject: your final presentation Steve, Drew, I would like you to email me a copy of the presentation slides you used today. It sounds like Alison is happy that you ruled out the hypothesis that green cells are somehow different from nongreen cells. That is great news. You've both done a lot of work this semester and that's good too. Your talk was difficult to understand and follow, for both Alison and the other members of the class, for a number of reasons: 1. you did not get the scientific terminology right - even to the point that Alison felt she had to jump in to correct it. Making an error at this "superficial" level undermines the audience's confidence that your deeper work is error-free. 2. you stumbled over basic statistical information also. E.g. when Alison asked "How do I read a density plot?"; this info should be at the fingertips of a first year student. Or when April asked about some details of your ANOVA fits at different points (residual analyses, exact nature of models tested...); this should be at the fingertips of someone who is deeply involved in the data analysis. Some of this I chalk up to nervousness, which I think would be greatly helped with more practice before presentation (see #3 below). 3. you both seemed rushed and unpracticed (both stumbling over material, and choosing convenient generic or colloquial words, sentences, or phrases instead of deliberately chosen, sharply informative ones) in your presentation. That can happen because of nervousness. However nervousness, rushing, stumbling, word choice, etc., can all be helped by practicing a talk *a lot* before presenting it "live". It doesn't matter whether other people practice their talks or not; what matters is that your presentation would greatly improve with practice. 4. graphs (especially but not only density plots) were unlabelled or labelled in unhelpful ways. E.g. we do not care what binwidth was used in nonpar density estimation in a presentation like this; we care what the variable is, what units it is measured in, etc. 5. very many slides had p-values without (a) saying what statistical test was involved; or (b) saying what scientific hypothesis was being tested. Audience lost. 6. The idea of pairing p-values for ANOVA's with density plots of data in the different cells was interesting and potentially very useful. However not enough information was provided on the slides, and you were not able to clarify well verbally when questions arose. So this ended up being confusing instead of helpful. Good idea, now well supported by your presentation. 7. presentation of mixture models was very confusing. I did not understand the use of K-S test to argue that 5-component mixture was better than kernel-smoothed density estimate; if this is what you did it is a misuse of the test (assumptions not even approximately met). in the end I could not tell from your talk what purpose was served by fitting mixture models. 9. green vs nongreen: - it wasn't at all clear to me what the point of this comparison was, until I asked Alison. Should be celar in your presentation. - the negative results in the cases that there were only 1 or 2 green cells are probably all due to lack of power. If you intend to keep these results, an estimate of power would also need to be included. - the results in the normal group where there were more green cells was more informative, I thought. One other note, related to the 'mixture modeling' portion of the talk: for unequal sample sizes per cell, if the different sample sizes per cell were not related to biology but rather were related to operator schedule and other external factors, I would be tempted to do at least one set of analyses using equal sample sizes per cell (by omitting later readings from cells with copious readings). I am glad that Alison is interested enough in your results to want to follow up with you in a couple weeks after you have turned in your final report. I hope that you are able to use the suggestions above, not only to think about the talk you gave, but also to improve your final paper for the course (and for Alison). Best, -BJ